MDAI is a substance that is not controlled by the Misuse of Drugs Act, so is legitimately described as a ‘legal high’. It is also still used in scientific research. Most of the MDAI is sold online and has been since 2009. MDAI is chemically derived from the drug MDA, which has been around since the 40s, and was popularly used in the 60s (See MDA section). MDAI is a drug where very little research has been conducted on its potential adverse effects and addictive properties. Please refer to the ‘research chemicals’ page for more information on these chemicals.