Methylone is thought to inhibit serotonin, norephephrine (noradrenaline) and dopamine reuptake, which produces an increase in these neurotransmitters. Reuptake of a neurotransmitter involves recycling it back into the storage section of the neuronal cell to be used again later. Inhibiting this reuptake process maintains the neurotransmitter within the synaptic space and allows the effects to continue. Furthermore, although methylone has an affinity for (ability to bind to) the serotonin transporter, it is 3 times less than MDMA, whereas the affinity for norepinephrine and dopamine transporters are similar.